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Cat. No. | Product Name | Target | Signaling Pathways |
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T38107 |
JJH260
JJH260 |
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JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 μM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 μM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysa... |
Cat. No. | Product Name | Species | Expression System |
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TMPH-00933 |
ADTRP Protein, Human, Recombinant (His & Myc)
Fatty acid esters of hydroxy fatty acids hydrolase ADTRP,FAH... |
Human | E. coli |
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system. |